Neonatal Encephalopathy Registry

Vermont Oxford Network established the Neonatal Encephalopathy Registry (NER) for newborn infants with encephalopathy and those treated with hypothermia born in 2006 to 2012. The NER identified demographic characteristics, associated perinatal factors, medical treatments, comorbidities, and outcomes of enrolled infants. It allowed us to evaluate variations in practice, monitor the introduction and dissemination of new neuroprotective therapies such as hypothermia, and assess selection criteria for neuroprotective therapy. The NER allowed us to identify opportunities for improvement in the quality and safety of care for infants with encephalopathy, define important questions for clinical research, and plan prospective research and randomized trials.

Publications

Barnette AR, Horbar JD, Soll RF, Pfister RH, Nelson KB, Kenny MJ, Raju TN, Bingham PM, Inder TE. Neuroimaging in the evaluation of the newborn brain. Pediatrics. 2014;133: e1508-e1517. PubMed: 24864165

Nelson KB, Bingham P, Edwards EM, Horbar JD, Kenny MJ, Inder T, Pfister RH, Raju T, Soll RF. Antecedents of neonatal encephalopathy in the Vermont Oxford Network Neonatal Encephalopathy Registry. Pediatrics. 2012; 130(5): 878-886. PubMed: 23071210

Pfister RH, Bingham P, Edwards EM, Horbar JD, Kenny MJ, Inder T, Nelson KB, Raju T, Soll RF. The Vermont Oxford Neonatal Encephalopathy Registry: rationale, methods, and initial results. BMC Pediatrics. 2012; 12(1): 84. PubMed: 22726296

Publications Citing NER Data

American College of Obstetricians and Gynecologists and American Academy of Pediatrics. Neonatal Encephalopathy and Neurologic Outcome, Second Edition. Washington, D.C.: American College of Obstetricians and Gynecologists, 2014.

NER Manuals and Data Forms

2012
NER Manual of Operations, Version 6.1
NER Booklet, Version 6.1 (Data Forms)

2011
NER Manual of Operations, Version 5.0
NER Booklet, Version 5.0 (Data Forms)

Follow-up for Neonatal Encephalopathy Registry
NER Follow-up Manual of Operations
NER Follow-up Sample Consent Form
NER Follow-up Data Forms